B vitamins are usually functioning as a precursor of coenzymes and prosthetic groups of enzymes. For example, TPP, FMN and so on.These vitamins are essential for cell functions, several physiological events, and in the metabolism of various neurotransmitters and neurohormones such as serotonin, dopamine, acetylcholine etcCertain B vitamin support nerve regeneration process (B1,B6 and B12. These vitamins are common called NEUROTROPHIC B vitamins, which constantly protect nerves against damaging environmental influences.B12 helps in promoting functional recovery, axonal regeneration, attenuate edema and myelin sheath regeneration after sciatic injury. B6 helps in balancing nerve metabolism and,B1 acts as a site-directed antioxidant.