Working closely with clinical pharmacometricians, physicians and other scientists, you will apply your expertise and leadership skills to contribute to the strategy of the clinical program and the design and interpretation of clinical studies. You will influence key decisions in early and late phases of clinical development.
In collaboration with clinical pharmacometricians, you will represent CPQP in cross-functional project teams, and be responsible for developing the clinical pharmacology strategy. The work includes integration of relevant data, such as dose information, pharmacokinetics, biomarkers and clinical endpoints within and across studies, compounds and development stages. You will take part in finding opportunities to apply model informed drug development to accelerate and advise decision making. You will communicate your findings within and outside of AstraZeneca and publish in peer reviewed journals.
The seniority of the role can depend and be adjusted depending on your previous experience and skills.
Essential for the role
PhD or equivalent (M.Sc/Pharm.D.) level expertise in a relevant field
At least 2+ years of industry experience or equivalent in pharmacokinetics, clinical pharmacology and application of modelling & simulation in different phases of drug development
Strong background in, and a clear understanding of clinical pharmacology aspects of drug development, preferably in both a small and large molecule settings
Solid knowledge of pharmacokinetics, its clinical application and regulatory context
Knowledge and experience in use of PK and PKPD modelling applied to life sciences
Biological understanding of disease and drug action
Good oral and written communication skills
Desirable in the role
Track record in creating and delivering on clinical pharmacology strategies of both small and large molecules
Early and late phase clinical development experience
Recognized clinical pharmacology expertise as demonstrated by scientific publishing in the field of clinical pharmacology
