Charles River are looking for a dynamic and influential in vivo/in vitro Pharmacologist.   The role is primarily based at our Harlow or Chesterford Research Park site, although you will be expected to interact with teams distributed across other Charles River sites (UK, Europe and USA), and with a diverse range of clients across the world.
In this role you will sit at the interface between the in vitro drug discovery teams, Clients and the in vivo pharmacology teams.   You will be a key member of our multidisciplinary drug discovery team, providing strong scientific leadership to multiple projects and project teams, ensuring work is completed to a high standard.  The successful candidate will work closely with our Clients and Business Development team with regards to securing new business through establishing client needs and providing guidance as to how to achieve project goals.  You will also suggest and design new in vivo studies, as well as interpret the outcome of completed pharmacological studies within the drug discovery cascade.  

Main tasks & responsibilities: 

•    Work with clients, Business Development specialists and Client Services to understand the needs of potential clients and design (and price) studies that meet their needs
•    Oversee in vivo FFS studies within Charles River to cover aspects such as resourcing and scheduling of studies to ensure timely delivery of data
•    Provide scientific and project leadership to drive our Client drug discovery programs 
•    Ensure any new models and variants on existing models are validated to the clients' expectations prior to studies being run for clients
•    To maintain a comprehensive understanding of relevant scientific literature and its applicability to ongoing projects
•    To be able to work independently and as part of a team, to solve complex problems 
•    To mentor and coach other scientists in achieving their potential and advancing their careers 
•    Leading by example delivering CRL's core values; Care, lead, own and collaborate
•    To regularly interact with existing clients to ensure work is being performed to an acceptable standard, and to rationalize, plan and perform requests for additional project work as appropriate.

•    Experience of the drug development process and be able to design a screening cascade
•    A track record of working on drug discovery programmes, preferably to development candidate selection
•    A broad understanding of the in vivo PD and disease model landscape  
•    The ability to design and interpret in vivo model data, and to put data into context with PK 
•    A track record in leading and motivating projects and teams in a drug discovery setting 
•    A dynamic and flexible approach towards achieving client-based objectives and meeting challenging deadlines
•    The ability to communicate confidently and effectively with clients and other Charles River sites via videoconferences, presentations and written reports.
•    Experience in the Respiratory therapeutic area would be advantageous (inhaled and oral delivery route and limitations of PD models for respiratory disease)