Coppell, TX, USA
Posted by: Astra Zeneca
20 Jun
19 Aug expires

Senior Process Engineer- Operations

Coppell, TX, USA
Job Description

As the Senior Process Engineer, you will bring relevant experience from pharmaceutical chemical processing or a large scale chemical manufacturing facility to manage, execute, and deliver new capital and non-capital projects, participate in design and safety reviews, interact and collaborate with other disciplines including external contractors, coach and mentor junior engineers, and provide technical leadership within the process engineering team. May be asked to support investigations and correction of process related problems and deviations from standards.

  • Develops conceptual strategies, processing schemes, feasibility studies, PFD’s, and detailed scopes of work

  • Develops, reviews, and communicates detailed process design, including P&ID mark-ups, equipment process data sheets, process piping design, and ancillary equipment

  • Works on several different projects and prioritizes these projects with guidance

  • Assists in developing control strategy and instrument process design, including emergency and shutdown procedures, instrument specification sheets, control ranges, and alarm points

  • Designs studies, executes experiments and perform data analysis

  • Writes study proposals, progress reports, development reports, user requirements, and various technical memos

  • Evaluates new technologies to improve the commercial production process

  • Supports scale up activities from R&D to production

  • Supports buildout of new facilities

  • Provides required documentation to support compliance

  • Supports the assurance of a robust manufacturing process for the current registered process as experience is gained post launch

  • Sets up robust process for trouble shooting

  • Acts as an effective change agent

  • Actively participates in the development and mentoring of additional staff

Job ID Reference
Desired Skills & Experience
  • Bachelor’s degree in Chemical Engineering or related discipline, plus a minimum of 5 years of direct chemical processing experience preferably in a pharmaceutical production environment

  • Experience in process design, project management, and leading a team

  • Hands-on experience in working with Chemical Operations and preferably API Manufacturing

  • Experience in reading/writing P&ID’s, Process Flow Diagrams, and mass and energy balances

  • Experience in batch type operations

  • Experience with large scale, high volume operations

  • Demonstrated leadership skills

  • Understanding of drug product supply chain needs

  • Experience in the following areas: Process Chemistry scale up; validation activities for commercial production; reactors and drying processes; and, setting up new equipment trains – (URS, PID, DQ, IQ, OQ, PQ)


Desirable for the role:

  • Capital project experience (CAPEX)

  • High temperature and high pressure applications

  • Experience with pressure filter dryer technology

  • Root cause investigation training

  • Lean certification

  • Six-sigma certification

  • Experience with automatic process controls (PLC, DCS)

  Gaithersburg, Maryland, USA
AstraZeneca is an exciting global, innovation-driven biopharmaceutical company. We’re inspired by what science can do. Driven by the desire to meet unmet patient needs in our core therapeutic areas. Bold in our thinking. Proactive in pursuing discoveries beyond imagination. At sites across the world, we bring teams together in a spirit of collaboration to turn great ideas into life-changing medicines – strengthening our product portfolio and harnessing the potential of a pipeline across all stages of the drug development process.
You’ll be part of a team that’s rolling back the frontiers of science to turn yesterday’s impossible into the normal of tomorrow. So, if you share our focus and passion, join us and make a difference to patients – and in return, we’ll help you develop way beyond what you thought possible.
 Coppell, TX, USA