We are currently looking for lead analytical pharmaceutical development scientists in chemical development with scientific project-based experience. Join one of our Chemical Development teams within Pharmaceutical Technology and Development (PT&D), at our Macclesfield Campus, UK.
Pharmaceutical Technology and Development (PT&D) are the bridge, which turns forward-thinking science into actual medicines that help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devices required to support new medicines – from supplies for use in early toxicology studies and clinical trials to developing the technology to ensure drugs can be scaled up for commercial manufacture.
You will join a vibrant team that is working on the next generation of medicines and play a key role in the analytical development of new medicinal products. We will rely on you to bring a strong analytical perspective to multi-disciplinary project teams and to help lead the early and late stage development of drug substances. You will be responsible for using science and innovation to deliver analytical knowledge that encompasses understanding of manufacturing processes, control strategy and robustness. We would like you to work independently and to lead interactions within cross functional teams, including with Process Chemists, Engineers, Contract Manufacturing Organisations (CMOs), Product Development, Regulatory CMC, Quality Assurance and Supply Chain.
As part of a global company with a focus on developing its people, you will have the opportunity to develop both personally and professionally while helping to deliver medicines that help millions of patients worldwide.
Leading API analytical activities to support project progression from clinical development phases through to late development and commercialisation
Developing API analytical control strategies, keeping a strong focus on quality for our patients
Identifying and solving potential analytical project issues
Planning and conducting lab-based experimental work in accordance with project timelines
Supporting the technical development of other scientists
Collaborating with internal and external manufacturing partners to deliver the analytical aspects of GMP API manufacture
Keeping abreast of scientific developments and proactively applying existing and novel approaches to projects
Authoring the CMC components of regulatory submissions and preparation of successful regulatory responses
Required Qualifications, Skills, Knowledge and Experience:
A degree (BSc, MSc or equivalent) in Chemistry or Analytical Chemistry with a proven track record of analytical development in a pharmaceutical environment, or a PhD including aspects of analytical measurement
Knowledge and practical experience across a range of analytical techniques, e.g. LC, MS, GC, NMR
Scientific leadership skills and the ability to use knowledge and experience to assess options available and deliver robust scientific contributions to projects
Strong problem-solving skills, underpinned by strong practical laboratory experience
Experience of working collaboratively within a mixed skill technical team, and ability to develop and utilise networks
Ability to communicate complex scientific information in a clear, concise and understandable way
Desirable Skills, Knowledge and Experience:
Ability to confidently and successfully lead improvement projects
Strong influencing, planning and prioritisation skills to ensure project delivery to deadlines
Experience of leading technical teams, coaching and people development
Commitment to improvement and innovation and knowledge of Lean principles
Knowledge and practical experience of quality and regulatory requirements (GMP and ICH) and health and safety requirements
