Charles River are looking for a Senior Scientist in DMPK Bioanalysis to grow our DMPK function, based at our Cambridge site in the UK.  Individuals should have a desire to develop their skills and knowledge; at Charles River we value the contributions individuals bring to the team so whether your focus is in-depth practical skills or expert DMPK drug discovery project support, the varied nature of our work offers opportunities to develop these.

•    Demonstrated practical knowledge of bioanalytical techniques within ADME/DMPK with hands on experience of bioanalytical method development and quantification of small molecules in complex matrices in a drug discovery setting
•    Demonstrated experience of pharmacokinetic parameter determination and an understanding of the underlying principles  
•    The desire and expertise to tackle challenging analytes, driving your efforts to a successful outcome. 
•    An understanding of the approaches taken to identify metabolites in biological matrices
•    A knowledge of the principles of PK/PD and PB/PK based modelling and simulation
•    Comprehensive trouble-shooting skills
•    An interest in new technology; an understanding of recent advances in bioanalysis, and how mass spectrometry can be applied to drug discovery outside of traditional DMPK studies
•    Attention to detail; getting it right the first time and quality control are at the heart of what we do
•    Strong organization and time management skills alongside an inbuilt flexibility to adapt to change
•    Excellent communication skills and be an effective team player; these will be essential to successful execution of projects whilst working in a matrix and multi-skilled environment.