Gaithersburg, MD, USA
Posted by: Astra Zeneca
05 Dec

Senior Scientist – In vitro immunology for cell therapy

Gaithersburg, MD, USA
Job Description

Building on your background in immunology you will apply your skills in a regenerative medicine setting, working collaboratively with project leaders, in vitro and in vivo scientists and therapy area specialists to ensure efficient progress of Cell Therapy projects and to drive our scientific capabilities.  The role is focused on laboratory-based activities and you will use your scientific expertise to design and execute experiments and to deliver high quality data. 


You will play a leading role in developing our scientific capabilities and presenting your work both internally and externally, working in a highly cross disciplinary environment with local and international colleagues.  


In this role it is essential to have good social and communication skills, be collaborative and a strong team player. You should be able to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude. Accountabilities include: 

  • Design and execute experiments to generate high quality, relevant data 

  • Independently assess and report data to support project decisions and milestones 

  • Communicate and share relevant information between distinct projects within the bioscience department as well as across other functions and externally  

  • Keep up to date with relevant scientific literature and technology platforms as well as writing and publishing scientific papers 

Job ID Reference
Desired Skills & Experience
  • Ph.D. in Cell Biology or a related discipline, or a MSc degree with relevant academic or industrial experience. 

  • Strong background in immunology, hands-on experience with developing CAR-T, NK, Treg or other immune cell therapy development preferred 

  • Proficiency in assays interrogating immune cell function, such as cellular activation, cytokine release, proliferation, cytotoxicity, multi-parameter flow cytometry, ELISA/MSD. 

  • Experience with immune cell expansion protocols strongly preferred. 

  • Preferred to have experience editing primary immune cells (e.g. CRISPR technology, Lenti-viral transduction). 

  • Good scientific presentation skills and ability to comfortably present and discuss scientific data. 

  • Good communication skills, a collaborative mindset and a strong team player. 

  • Ability to work independently, take own initiatives and have a positive, goal-oriented and problem-solving attitude. 

  Gaithersburg, Maryland, USA
AstraZeneca is an exciting global, innovation-driven biopharmaceutical company. We’re inspired by what science can do. Driven by the desire to meet unmet patient needs in our core therapeutic areas. Bold in our thinking. Proactive in pursuing discoveries beyond imagination. At sites across the world, we bring teams together in a spirit of collaboration to turn great ideas into life-changing medicines – strengthening our product portfolio and harnessing the potential of a pipeline across all stages of the drug development process.
You’ll be part of a team that’s rolling back the frontiers of science to turn yesterday’s impossible into the normal of tomorrow. So, if you share our focus and passion, join us and make a difference to patients – and in return, we’ll help you develop way beyond what you thought possible.
 Gaithersburg, MD, USA