Cushing syndrome is a rare disease caused by the overproduction of cortisol, a hormone that regulates metabolism and our response to stress. Researchers at the Eunice Kennedy Shriver National Institute of Child Health & Human Development conduct research on Cushing syndrome, including clinical trials. Learn more about NICHD: https://www.nichd.nih.gov. For a text alternative of the video, visit: https://www.nichd.nih.gov/newsroom/digital-media/videos/cushing-syndrome.